Calcium-binding protein 8 is a protein with high similarity to the calcium-binding proteins of the calmodulin family.
The encoded protein contains two EF-hand domains and potential calcium-binding sites.
Alternative splicing results in multiple transcript variants.
Calneuron 1 negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity.
May play a role in the physiology of neurons and is potentially important in memory and learning.
Interacts with PI4KB.
This binding competes with FREQ/NCS1 binding in a calcium-dependent manner.
The mouse orthologous gene (Caln1) shows little prenatal expression, with highest expression at Postnatal Day 21.
I CALN1 has a significant role in the physiology of neurons and is potentially important in memory and learning.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human CALN1.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Met1-Ser192 of human CALN1, fused to two N-terminal Tags, His-Tag and T7-tag, expressed in E. coli.
