Calmodulin (CaM) (an abbreviation for CALcium MODULated proteIN) is a calcium-binding protein expressed in all eukaryotic cells.
It can bind to and regulate a number of different protein targets, thereby affecting many different cellular functions.
Calmodulin 1 is one of nearly twenty human calmodulins.Calmodulinis the archetype of the family of calcium-modulated proteins of which nearly 20 members have been found.
They are identified by their occurrence in the cytosol or on membranes facing the cytosol and by a high affinity for calcium.
Calmodulin contains 148aa and has 4 calcium-binding motifs.
Its functions include roles in growth and the cell cycle as well as in signal transduction and the synthesis and release of neurotransmitters.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.