CACNa1H encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex.
Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio.
The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell.
There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts.
Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here.
Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE).
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilutions:Western Blot: 0.5-2ug/mlImmunohistochemistry (Paraffin): 5-20ug/ml Immunocytochemistry: 5-20ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
Specificity：Recognizes mouse CACNa1H. Species Crossreactivity: rat
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Mo Rt
Immunogen：Recombinant protein corresponding to Ser2160-Val2359 of mouse CACNa1H, expressed in E. coli
