The eighth component of complement (C8) consists of 3 nonidentical subunits arranged asymmetrically as a disulfide-linked alpha-gamma dimer and a noncovalently associated beta chain.
Genetic studies of C8 polymorphisms established that alpha-gamma and beta are encoded at different loci.
Implicit in this finding was the existence of 2 different genes and the likelihood that alpha-gamma is synthesized as a single-chain precursor
The C8G belong to the lipocalin superfamily, a group of distantly related and similarly folded proteins that are able to carry small lipophilic molecules such as retinol, odorants, and steroids.
The lipocalin superfamily has a very ancient origin since lipocalins are found in arthropods as well as in vertebrates.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human C8g.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Lys39-Arg202 of human C8g fused to His-Tag and GST-tag at N-terminal expressed in E. coli
