84-4409-28 C1QTNF9 (C1q And Tumor Necrosis Factor Related Protein 9, CTRP9, C1QTNF9A, AQL1, Complement C1q and tumor necrosis factor-related protein 9A) 200ul 362337
84-4409-28 C1QTNF9 (C1q And Tumor Necrosis Factor Related Protein 9, CTRP9, C1QTNF9A, AQL1, Complement C1q and tumor necrosis factor-related protein 9A) 200ul 362337
CTRP9 shows the highest degree of amino acid identity to adiponectin in its globular C1q domain.
CTRP9 is expressed predominantly in adipose tissue and females expresses higher levels of the transcript than males.
CTRP9 is a secreted glycoprotein with multiple post- translational modifications in its collagen domain that include hydroxylated prolines and hydroxylated and glycosylated lysines.CTRP9 and adiponectin can be secreted as heterooligomers when cotransfected into mammalian cells, and in vivo, adiponectin/CTRP9 complexes can be reciprocally coimmunoprecipitated from the serum of adiponectin and CTRP9 transgenic mice.
Biochemical analysis demonstrates that adiponectin and CTRP9 associate via their globular C1q domain, and this interaction does not require their conserved N-terminal cysteines or their collagen domains.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes human C1QTNF9.
Isotype:IgG
Calc Applications Abbrev:E IC IHC WB
Calc Crossreactivity:Hu
Immunogen:Recombinant protein corresponding to Gln20-Pro333 of human C1QTNF fused to His-Tag and T7-tag at N-terminal expressed in E. coli.