Chemokine (C-X-C motif) ligand 7 (CXCL7) is a platelet-derived growth factor that belongs to the CXC chemokine family.
It is an isoform of Beta-Thromboglobulin or Pro-Platelet basic protein (PPBP).
Beta-thromboglobulin (B-TG) has a molecular weight of 35000 daltons and is a specific protein of platelets.
Composed of 4 identical subunits; It is synthesized in the cells as a biologically inactive 15kD precursor called PBP (platelet basic protein).
It is stored in the Alpha-granules of platelets and released in large amounts after platelet activation.It is a protein that is released in large amounts from platelets following their activation.
It stimulates various processes including mitogenesis, synthesis of extracellular matrix, glucose metabolism and synthesis of plasminogen activator.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:rat
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes rat bTG.
Isotype:IgG
Calc Applications Abbrev:E IC IHC WB
Calc Crossreactivity:Rt
Immunogen:Recombinant protein corresponding to Ile46-Ile107 of rat bTG, fused to His-Tag and T7-tag at N-terminal expressed in E. coli.