Bone morphogenetic protein 3 is a member of the transforming growth factor beta superfamily.
It, like other bone morphogenetic proteins (BMP's) is known for its ability to induce bone and cartilage development.
It is a disulfide-linked homodimer.
It negatively regulates bone density.
BMP3 is an antagonist to other BMP's in the differentiation of osteogenic progenitors.
It is highly expressed in fractured tissues.
Negatively regulates bone density.
Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification.
Highly expressed in fracture tissue, particularly in osteoblasts, osteoclasts and chondroblasts.
Expressed in adult and fetal cartilage.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human BMP3.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Arg373-Arg472 from human BMP3 fused to two N-terminal Tags, His-Tag and GST-tag, expressed in E. coli.
