84-4408-50　［受注停止］BCAS3 (Breast Carcinoma Amplified Sequence 3, GAOB1, MAAB, GAOB1) 200ul　362260

特徴

• The BCAS3 gene is regulated by estrogen receptor alpha (ER-alpha).
• The PELP1 protein acts as a transcriptional coactivator of estrogen receptor induced BCAS3 gene expression.
• In addition BCAS3 possesses histone acetyltransferase activity and itself appears to act as a coactivator of ER-alpha.
• Furthermore BCAS3 requires PELP1 to function as a coactivator in ER-alpha.
• The deduced 913aa protein has a calculated molecular mass of 99kD.
• Northern blot analysis revealed a 3.9-kb transcript expressed in all tissues examined.
• Several smaller transcripts showed tissue-specific distribution.
• Multiple tissue expression array analysis indicated ubiquitous expression, with highest levels in stomach, liver, lung, kidney, fetal kidney, prostate, testis, thyroid gland, and adrenal gland.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- M NPIALGSRWL AYAENKLIRC HQSRGGACGD NIQSYTATVI SAAKTLKSGL TMVGKVVTQL TGTLPSGVTE DDVAIHSNSR RSPLVPGIIT VIDTETVGEG QVLVSEDSDS DGIVAHFPAH EKPVCCMAFN TSGMLLVTTD TLGHDFHVFQ ILTHPWSSSQ CAVHHLYTLH RGETEAKVQD ICFSHDCRWV VVSTLRGTSH VFPINPYGGQ PCVRTHMSPR VVNRMSRFQK SAGLEEIEQE LTSKQGGRCS PVPGLSSSPS GSPLHGKLNS QDSYNNFTNN NPGNPRLSPL PSLMVVMPLA QIKQPMTLGT ITKRTG
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.