84-4408-47　［受注停止］BCAN (Breast Cancer Anti-Estrogen Resistance 1, CAS, CRKAS, P130Cas, CASS, Crk-Associated Substrate, Cas Scaffolding Protein Family Member 1) 200ul　362257

特徴

• BCAR1, or CAS, is an Src family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion.
• The predicted 870aa BCAR1 protein has a calculated mass of 93kD.
• BCAR1 contains an SH3 domain in its N-terminal part, multiple potential tyrosine phosphorylation sites in its central part, and a proline-rich stretch in its C-terminal part
• BCAR1 shares 91% amino acid identity with rat and mouse p130Cas.
• SDS-PAGE and Western blot analyses demonstrated that BCAR1 encodes a 116kD protein; the mouse and rodent p130Cas proteins exhibit the same size.
• BCAR1 transcript in all tissues tested, with highest expression in testis and low expression in liver, thymus, and peripheral blood leukocytes.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.