Aristaless related homeobox, also known as ARX is a protein associated with mental retardation and lissencephaly.
The expressed protein contains two conserved domains, a C-peptide (or aristaless domain) and the prd-like class homeobox domain.
It is a member of the group-II aristaless-related protein family whose members are expressed primarily in the central and/or peripheral nervous system.
This gene is involved in CNS and pancreas development.
This gene is involved in CNS and pancreas development
Expressed predominantly in fetal and adult brain and skeletal muscle.
Expression is specific to the telencephalon and ventral thalamus.
There is an absence of expression in the cerebellum throughout development and also in adult.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes human ARX.
Isotype:IgG
Calc Applications Abbrev:E IC IHC WB
Calc Crossreactivity:Hu
Immunogen:Recombinant protein corresponding to Ser25-Asp246 of human ARX, fused to two N-terminal Tags, His-Tag, T7-tag expressed in E. coli.