84-4407-46　APOC4 (Apolipoprotein C4, Apo-C4, Apolipoprotein C-IV) 200ul　362157

特徴

• Allan et al.
• (1995) identified and characterized a previously unreported human gene located within the previously known cluster of apolipoprotein genes on chromosome 19: APOE, APOC1, and APOC2.
• On the basis of its location and its properties, the new gene was designated APOC4.
• Nucleotide sequence analysis of genomic DNA and liver cDNA clones revealed a 3.3-kb gene consisting of 3 exons and 2 introns.
• Its 3-prime terminus lies 555 bp upstream of APOC2, giving the 2 genes the same transcriptional orientation.
• The promoter of the APOC4 lacks a typical TATA box, consistent with an apparent heterogeneity in transcription start sites.
• RNase protection analysis indicated relatively low apoC-IV mRNA levels in human liver, compared to apoC-II mRNA levels.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• AA Sequence:MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTGGG SGIEGRGSMG YRGSEF-MST ESLSPTPGPE SSRWSLVRAR VLEMVEPLVT RTRDRWQWFW GPGAVQGFMQ TYYEDHLKDL GPRTQAWLQS SRDHLLNKTH SLCPRLLCKD RTQG
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.