Amyloid beta A4 precursor protein-binding family A member 3 is member of the X11 protein family.
It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein.
This gene product is believed to be involved in signal transduction processes.
This gene is a candidate gene for Alzheimer's disease
Alzheimer disease (AD) is a progressive neurodegenerative disorder that is characterized by dementia, neuronal loss, and accumulation in the brain of extracellular beta-amyloid fibrils and intraneuronal neurofibrillary tangles.
The major components of amyloid plaques are 40- to 42aa beta-amyloid peptides (A-beta), which are derived from beta-amyloid precursor protein (APP) via proteolytic processing.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes mouse APBA3.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Mo
Immunogen：Recombinant protein corresponding to Val261-Leu506 of mouse APBA3, fused to two N-terminal Tags, His-Tag and T7-tag, expressed in E. coli.
