84-4407-13　ANP (Atrial Natriuretic Peptide, ANH, ANF, PND, NPPA, CDD-ANF, Atrial Natriuretic Factor, Atrial Natriuretic Hormone, Atriopeptin, Natriuretic Peptide Precursor A, Prepronatriodilatin, Cardiodilatin-related peptide) 200ul　362124

特徴

• Atrial natriuretic peptide (ANP),is a polypeptide hormone involved in the homeostatic control of body water, sodium, and adiposity.
• It is released by atrial myocytes, muscle cells in the atria of the heart, in response to high blood pressure.
• ANP acts to reduce the water, sodium and adipose loads on the circulatory system, thereby reducing blood pressure.
• ANP is a 28aa peptide with a 17aa ring in the middle of the molecule.
• The ring is formed by a disulfide bond between two cysteine residues at positions 7 and 23.
• ANP is closely related to BNP and CNP which all share the same amino acid ring.
• ANP was discovered in 1981 by a team in Ottawa led by Adolfo J.
• de Bold after they made the seminal observation that injection of atrial (but not ventricular) tissue extracts into rats caused copious natriuresis.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• AA Sequence:MHHHHHHSSG LVPRGSGMKE TAAAKFERQH MDSPDLGTDD DDKAMADIGS EF-NPVYGS VSNADLMDFK NLLDRLEDKM PLEDEAVPSQ VLSEQNEEAG APLSPLSEMP PWMGEVNPAQ REGGVLGRGP WESSDRSALL KSKLRALLTA PRSLRRSSCF GGRMDRIGAQ SGLGCNSFRY RR
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.