84-4405-95　ADCY1 (Adenylate Cyclase 1, Brain, AC1, ATP pyrophosphate-lyase 1, Ca(2+)/calmodulin- activated adenylyl cyclase, Adenylate cyclase type I) 200ul　362008

特徴

• Adenylate cyclase type 1 is aform of adenylate cyclase expressed in brain.
• A similar protein in mouse is involved in pattern formation of the brain.
• The neural-specific, calmodulin-sensitive adenylyl cyclase (type I), which was first cloned from bovine brain, has been implicated in learning and memory
• Villacres et al.
• (1993) cloned the gene for human fetal brain type I adenylyl cyclase.
• By database analysis and PCR of human embryonic kidney cell cDNA, Ludwig and Seuwen (2002) cloned full-length ADCY1.
• The deduced protein contains 1,119aa.
• Semiquantitative RT-PCR detected ADCY1 highly expressed in peripheral blood leukocytes.
• Moderate or low ADCY1 levels were detected in brain and most other tissues examined except thymus, prostate, and small intestine.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- ILFADIVG FTGLASQCTA QELVKLLNEL FGKFDELATE NHCRRIKILG DCYYCVSGLT QPKTDHAHCC VEMGLDMIDT ITSVAEATEV DLNMRVGLHT GRVLCGVLGL RKWQYDVWSN DVTLANVMEA AGLPGKVHIT KTTLACLNGD YEVEPGHGHE RNTFLRTHNI ETFFIVPSHR RKIFPGLILS DIKPAKRMKF KTVCYLLVQL MHCRKMFKAE IPFSNVMTCE DDDKRRALRT ASEKLRNRSS FSTNVVYTTP GTRVNRYIS
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.