Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton.
In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified
Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in nonmuscle cells.Defects in ACTG1 are the cause of non-syndromic sensorineural deafness autosomal dominant type 20 (DFNA20); also called autosomal dominant deafness type 26 (DFNA26)
DFNA20 is a form of sensorineural hearing loss.
Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human ACTg1.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Rb
Immunogen：Recombinant protein corresponding to Met1-Phe375 of human ACTg1, fused to two N-terminal Tags, His-Tag and GST-tag, expressed in E. coli.
