Low molecular weight phosphotyrosine protein phosphatase belongs to the phosphotyrosine protein phosphatase family of proteins.
It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate.
This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate
This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes.
Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios.
Three transcript variants encoding distinct isoforms have been identified for this gene.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.