84-4405-18　A Disintegrin And Metalloprotease 12 (MCMP, MCMPMltna, MLTN, MLTNA, Meltrin Alpha, Disintegrin and metalloproteinase domain-containing protein 12) 200ul　361930

特徴

• ADAM12 encodes a member of the ADAM (a disintegrin and metalloprotease) protein family.
• Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis.
• This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form.
• Similarly to myogenin, a marker of early muscle differentiation, mouse meltrin-alpha is expressed in neonatal muscle and bone, and its expression increases dramatically in response to the induction of differentiation.
• Immunocytochemical localization and functional expression studies suggested that meltrin-alpha may be involved in myotube formation.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.