84-4405-17　A Disintegrin And Metalloprotease 1 (FTNAP, PH-30a, Ftna, ADAM1P, Fertilin Alpha, Disintegrin and metalloproteinase domain-containing protein 1) 200ul　361929

特徴

• ADAM is a family of peptidase proteins.
• It is also known as the adamalysin family.
• ADAMs are classified as sheddases because they cut off or shed extracellular portions of transmembrane proteins
• The human fertilin alpha gene is non-functional: implications for its proposed role in fertilization.In the guinea-pig, the alpha subunit of the fertilin complex, a heterodimeric surface membrane glycoprotein found on the head region of spermatozoa, has previously been proposed to mediate membrane fusion with the oolemma plasma membrane during fertilization.
• The only fertilin alpha-like gene in humans is an expressed, but nonfunctional, pseudogene, possibly derived by genetic recombination between the two fertilin alpha genes found in some primates.
• This finding clearly raises questions about the importance and/or role of fertilin alpha in mammalian fertilization.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.