Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression.
The majority of zinc-finger proteins contain several Krüppel-type DNA binding domains that are frequently observed to be involved in sequence-specific DNA binding.
ZNF441 is a 626aa transcriptional regulator belonging to the Krüppel C2H2-type zinc-finger protein family.
ZNF441 localizes to the nucleus and contains 19 C2H2-type zinc fingers.
ZNF441 is encoded by a gene located on chromosome 19, which contains a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes.
Chromosome19 is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and FcR.
Key genes for eye color and hair color also map to chromosome 19.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 15mM sodium azide.
Specificity：Recognizes human ZNF441. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to residues in human ZNF441.
