Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression.
The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins.
ZNF232, also known as Zinc finger and SCAN domain-containing protein 11, is a 417aa protein belonging to the Krüppel C2H2-type zinc-finger protein family.
Localized to the nucleus, ZNF232 contains one SCAN box domain and five C2H2-type zinc fingers.
Due to the presence of these domains, ZNF232 may be involved in transcriptional regulation.
Ubiquitously expressed, ZNF232 is present at high levels in testis, liver and ovary.
ZNF232 exists as two isoforms produced by alternative splicing.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide.
Specificity:Recognizes human ZNF232. Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to human ZNF232.