84-4404-55　［取扱停止］ZDHHC17 (Palmitoyltransferase ZDHHC17 , Huntingtin Yeast Partner H, Huntingtin-Interacting Protein 14, HIP-14, Huntingtin-Interacting Protein 3, HIP-3, Huntingtin-Interacting Protein H, Putative MAPK-activating Protein PM11, Putative NF-kappa-B-activating Protein) 50ul　361472

特徴

• HIP3 (huntingtin-interacting protein 3), also known as ZDHHC17 (zinc finger, DHHC-type containing 17), HYPH, HIP14 or HSPC294, is a 632aa multi-pass membrane protein that localizes to both the golgi apparatus to cytoplasmic vesicles and contains one DHHC-type zinc finger and five ANK repeats.
• Expressed predominately in brain tissue, but also present in kidney, pancreas, testis and heart, HIP3 functions as a palmitoyltransferase that is involved in the sorting and targeting of proteins that are involved in endocytotic events.
• HIP3 exists as multiple alternatively spliced isoforms and is associated with the pathogenesis of Huntington’s Disease (HD), a genetic neurological disorder that is characterized by uncoordinated, jerky body movements and a decline in some mental abilities.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.