84-4404-49　［取扱停止］ZBTB7A (Zinc Finger and BTB Domain-containing Protein 7A, Factor Binding IST Protein 1, FBI-1, Factor that Binds to Inducer of Short Transcripts Protein 1, HIV-1 1st-binding Protein 1, Leukemia/Lymphoma-Related Factor, POZ and Krueppel Erythroid Myeloid Ontogenic) 50ul　361469

特徴

• LRF, formerly identified as Pokemon, is a poxvirus zinc finger (POZ) domain-containing transcription factor that influences cell differentiation.
• LRF (for leukemia/lymphoma related factor) is also known as zinc finger and BTB domain containing 7A, ZBTB7, TIP21, FBI1 and FBI-1.
• POZ-domain transcription factors contain a POZ or BTB type protein-protein interaction domain at their N-terminus and Kruppel-type zinc fingers at their C-terminus.
• LRF is inducible during both murine and human preadipocyte differentiation and may contribute to adipogenesis through influencing the switch from cellular proliferation to terminal differentiation.
• LRF can associate with active chromatin and stimulate TAT-activated HIV-1 transcription through interactions with the HIV-1 long terminal repeat.
• 3T3L1 cells stably overexpressing LRF show a reduction in DNA synthesis and in expression of cyclin A, cyclin-dependent kinase 2 and p107.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.