XCL2 is a small cytokine belonging to the XC chemokine family.
Chemokines are a group of cytokines.
Members of this group of so-called C-Chemokines belong to the SCY family of cytokines and are designated XCL (L for ligand) followed by a number.
XCL2 is the new designation of SCM-1-beta.
XCL2 is highly related to another chemokine called XCL1.
XCL2 gene is located on chromosome 1 in humans.
XCL2 is predominantly expressed in activated T cells, but can also be found at low levels in unstimulated cells.
XCL2 induces chemotaxis of cells expressing the chemokine receptor XCR1.
XCL2 gene has been proposed to participate in pathways (Chemokine signaling pathway, Cytokine-cytokine receptor interaction) and processes (blood circulation, signal transduction, chemotaxis, immune response).
XCL2 are expected to have molecular function (chemokine activity) and to localize in various compartments (extracellular space, extracellular region).
A putative protein interactor has been described (XCR1).
The spliced mRNA putatively encodes a good protein, containing small cytokines (intecrine/chemokine), interleukin-8 like domain; the complete protein appears to be secreted.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide.
Specificity：Recognizes human XCL2. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to residues in human XCL2.
