84-4403-89　［取扱停止］VNN1 (Pantetheinase, Pantetheine Hydrolase, Tiff66, Vascular Non-inflammatory Molecule 1, Vanin-1, Vanin 1, Vanin1) 100ul　361437

特徴

• Hematopoietic precursor cells migrate to the thymus, where they differentiate into mature T lymphocytes.
• GPI-anchored vanin-1 protein regulates the late adhesion steps of thymus homing of bone marrow precursor cells.
• Vanin-1 is ubiquitously expressed as a pantetheinase enzyme and catalyzes the hydrolysis of pantetheine for vitamin B5 recycling.
• The hydrolytic activity of vanin-1 generates the potent antioxidant cysteamine as a metabolite.
• As a membrane bound pantetheinase, vanin-1 provides the main source of cysteamine under normal physiological conditions.
• In mice, vanin-1 is expressed specifically in male Sertoli cells of the developing testis, where it aids in cell migration.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.