The homeobox DNA-binding domain is a 60aa motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and the control of gene expression.
TSHZ2 (Teashirt homolog 2), also known as ZNF218 (Zinc finger protein 218) and OVC10-2 (Ovarian cancer-related protein 10-2), is a 1034aa nuclear protein that contains one homeobox DNA-binding domain, as well as five C2H2-type zinc fingers.
In drosophilia, teashirt genes function as region-specific homeotic genes that specify trunk identity during embryogenesis and these genes seem to conserve the same function in mice.
The gene encoding TSHZ2 maps to human chromosome 20, which comprises approximately 2% of the human genome and contains nearly 63 million bases that encode over 600 genes.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide.
Specificity：Recognizes human TSHZ2. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa818-863 of human TSHZ2.
