The Ox40 ligand, Ox40L (also designated gp34), is a type II membrane protein, due to the absence of a signal peptide.
Ox40L, a member of the tumor necrosis factor (TNF) superfamily, is a costimulatory molecule involved in dendritic cell:T cell interactions, T cell homing and B cell activation.
Engagement of Ox40L with its receptor, Ox40, delivers a strong costimulatory signal to effector T cells.
Ox40L is found preferentially on activated B cells and its receptor, Ox40, is a member of the tumor necrosis factor receptor (TNFR) family that is expressed on activated T cells.
Ox40L plays a critical role in antigen-specific T cell responses in vivo and in both the priming and effector phases of T cell activation when expressed on antigen-presenting cells (APCs).
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide.
Specificity：Recognizes human TNFSF4. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human TNFSF4.
