84-4402-35　［取扱停止］TNFSF14 (Tumor Necrosis Factor Ligand Superfamily Member 14, Herpes Virus Entry mediator Ligand, HVEM-L, Herpesvirus Entry mediator Ligand, CD258, Cleaved into the Following 2 Chains, Tumor Necrosis Factor Ligand Superfamily Member 14, Membrane Form) 50ul　361343

特徴

• Herpes virus entry mediator (HVEM), a type I transmembrane protein, is a member of the TNF receptor superfamily.
• HVEM mediates the entry of herpes simplex virus (HSV) 1 and 2 into T lymphocytes by serving as an attachment site for the HSV envelope glycoprotein D (gD).
• HVEM also binds two cellular ligands, secreted lymphotoxin a and light.
• LIGHT is a member of the TNF superfamily produced by activated T cells.
• This type II transmembrane protein competes with HSV glycoprotein D for binding to HVEM.
• LIGHT is closely related in sequence to lymphotoxin B (LTB) and can also bind to the LTB receptor.
• LIGHT is also known to induce apoptosis and suppress tumor formation.The gene encoding LIGHT maps to human chromosome 19p13.3.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.