TNF cytokine family member TALL-1 (also designated BAFF, zTNF4, THANK and BLYS) is a type II membrane protein that shares characteristics with other members of the tumor necrosis factor (TNF) cytokine family.
TALL-1 has the ability to bind to three receptors, TACI, BCMA and BAFF-R, but unlike other TNF receptors, BAFF-R specifically binds only the TALL-1 ligand.
The gene encoding human BAFF-R, which maps to chromosome 22q13.1-q13.31, is expressed at high levels in spleen and lymph nodes and at lower levels in peripheral blood leukocytes and thymus.
Expression of BAFF-R is crucial for selecting transitional B cells into the mature B cell pool.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 15mM sodium azide.
Specificity：Recognizes human TNFRSF13C.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to human TNFRSF13C.
