84-4402-10　［取扱停止］TMED10 (Transmembrane emp24 Domain-containing Protein 10, 21kD Transmembrane-trafficking Protein, S31III125, S31I125, Tmp-21-I, Transmembrane Protein Tmp21, p23, p24 Family Protein delta-1, p24delta1, p24delta, TMP21) 100ul　361324

特徴

• TMP21 (21kD transmembrane-trafficking protein), also known as TMED10 (transmembrane emp24 domain-containing protein 10), Tmp-21, S31I125, S31III125, p23 or p24d, is a member of the EMP24/GP25L/p24 cargo family of proteins that regulates vesicular trafficking in the early secretory pathway.
• TMP21 is a ubiquitously expressed single-pass type I membrane protein localizing to the Golgi cisternae and the plasma membrane.
• It contains one GOLD (Golgi dynamics) domain and participates in protein transport and quality control between the endoplasmic reticulum (ER) and the Golgi complex.
• In addition, TMP21 is a component of the heteromeric secretase complex (or Presenilin complex) and functions to regulate the ©-secretase activity.
• Two isoforms, namely TMP21-I and TMP21-II, exist for this protein.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.