The homeobox DNA-binding domain is a 60aa motif that is conserved among many species.
It also functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and control of gene expression.
TGIF2LY (TGFB-induced factor homeobox 2-like, Y-linked), also known as TGIFLY, is a 185aa testis-specific nuclear protein that functions as a transcriptional regulator during spermatid maturation.
TGIF2LY belongs to the TALE/TGIF homeobox family and contains one homeobox DNA-binding domain.
The gene encoding TGIF2LY maps within a male specific region of chromosome Y, in a region implied to form following a large X-to-Y transposition.
The C-terminal region of TGIF2LY differs from the C-terminal region of its chromosome X homolog TGIF2LX, which suggests that TGIF2LY may act as a competitor or regulator of TGIF2LX.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 15mM sodium azide.
Specificity：Recognizes human TGIF2LY. Species Crossreactivity: rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Rt
Immunogen：Synthetic peptide corresponding to human TGIF2LY.
