84-4401-76 [取扱停止]TFF1 (Trefoil Factor 1, Breast Cancer Estrogen-inducible Protein, PNR-2, Polypeptide P1.A, hP1.A, Protein pS2, BCEI, PS2) 50ul 361299
特徴
- Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing.
- These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain.
- pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa.
- pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach.
- pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells.
- pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties.
- The gene encoding pS2 maps to human chromosome 21q22.3.
- Applications:Suitable for use in Western Blot.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:50ul
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide.
- Specificity:Recognizes human TFF1. Species Crossreactivity: mouse and rat
- Isotype:IgG
- Calc Applications Abbrev:WB
- Calc Crossreactivity:Hu Mo Rt
- Immunogen:Synthetic peptide corresponding to human TFF1.
- Shelf Life:1year
- Swiss Prot Number:P04155
- EU Commodity Code:30021010
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