84-4401-69　［取扱停止］TESK2 (Dual specificity testis-specific Protein Kinase 2, Testicular Protein Kinase 2) 100ul　361295

特徴

• TESK2 (testicular protein kinase 2) is a nuclear protein that belongs to the protein kinase superfamily and is expressed in testis and prostate.
• Functioning as a dual specificity protein kinase, TESK2 catalyzes the ATP-dependent phosphorylation of substrates and autophosphorylation on tyrosine and serine/ threonine residues, thereby mediating intracellular signal transduction pathways.
• TESK2 requires magnesium as a cofactor and its catalytic activity is thought to play an important role in meiotic events such as spermatogenesis.TESK2 contains one protein kinase domain that is 65% identical to the kinase domain found in TESK1 (testicular protein kinase 1), suggesting a similar role for these proteins in phosphorylation events.
• Three isoforms of TESK2 are expressed due to alternative splicing.
• Applications:Suitable for use in Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.