Proper cell growth, differentiation and survival relies on a series of enzymes involved in complex redox and metabolic pathways.
One of these enzymes, Transaldolase, contributes to the generation of NADPH in the nonoxidative phase of the pentose phosphate pathway (PPP) and is important for maintaining metabolite balance.
In conjunction with several other enzymes, Transaldolase works to maintain the mitochondrial transmembrane potential by producing both ribose-5-phosphate and NADPH for use in nucleic acid and lipid biosynthesis.
The role of Transaldolase in the PPP of spermatoza is of significant importance, as deficiencies in Transaldolase are directly related with male infertility due to loss of sperm structure and function.
Mutations in the gene encoding Transaldolase are thought to play a role in multiple sclerosis and are the direct cause of hepatosplenomegaly and telangiectases of the skin.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide, 50% glycerol.
Specificity：Recognizes human TALDO1. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant protein corresponding to human TALDO1.
