84-4399-91　［取扱停止］SLC34A1 (Sodium-Dependent Phosphate Transport Protein 2A, Sodium-Phosphate Transport Protein 2A, Na(+)-Dependent Phosphate Cotransporter 2A, NaPi-3, Sodium/Phosphate Cotransporter 2A, Na(+)/Pi Cotransporter 2A, NaPi-2a, Solute Carrier Family 34 Member 1) 100ul　361195

特徴

• Renal tubular reabsorption of phosphate is critical to the maintenance of phosphate homeostasis in mammals.
• The brush-border membrane Na+/Pi cotransport systems in proximal tubules play a major role in this process.
• The renal Na(+)/P(i) cotransporter NPT2 is expressed in the brush border membrane (BBM) of proximal tubular cells.
• NPT2 gene expression is crucial for PTH effects on renal P(i) handling.
• However, renal expression of the sodium/phosphate cotransporter gene, NPT2, is not required for regulation of renal 1 alpha-hydroxylase by phosphate.
• NPT2 is an integral membrane protein expressed in kidney and lung.
• The gene encoding human NPT1 maps to chromosome 6q21.3-p23, while the gene encoding human NPT2 maps to chromosome 5q35.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.