84-4399-83　［取扱停止］SLC26A3 (Chloride Anion Exchanger, Down-regulated in Adenoma, Protein DRA, Solute Carrier Family 26 Member 3, DRA) 100ul　361191

特徴

• The SLC26 family comprises sulfate/anion transporter genes.
• SLC26 family members are well conserved in both their genomic and protein structures, yet have markedly different tissue expression patterns.
• Members of the SLC26 family can mediate the electroneutral exchange of Cl(-) for HCO(3)(-) across the plasma membrane of mammalian cells.
• Family members include SLC26A3 (also designated downregulated in adenoma), pendrin (SLC26A4), prestin (SLC26A5) and SLC26A6.
• SLC26A3 is a chloride/bicarbonate exchanger, involved in absorption in the colon.
• SLC26A3 interacts with PDZK1 and helps mediate electrolyte and fluid absorption.
• Defects in SLC26A3 are the cause of congenital chloride diarrhea.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.