The sodium-dependent vitamin C transporters SVCT1 and SCVT2 are membrane transporters for L-ascorbic acid (Vitamin C).
Both SVCT proteins mediate high affinity Na+-dependent L-ascorbic acid transport and are necessary for the uptake of vitamin C in many tissues.
SVCT1 is a 604aa protein that is expressed mainly in epithelial tissues, including intestine, kidney, and liver.
SVCT2 is a 592aa protein that shares 65% homology to SVCT1 and has been detected in various metabolically active cells as well as in specialized tissues such as eye and brain.
A non-functional splice variant of SVCT1 has been identified in normal human intestine.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol.
Specificity:Recognizes human SLC23A2. Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to human SLC23A2.