84-4399-30　［取扱停止］Septin 2 (DIFF6, hNEDD5, KIAA0158, Neural Precursor Cell Expressed Developmentally Down Regulated Protein 5, Pnutl3, Protein NEDD5, SEPT2) 50ul　361158

特徴

• The transcriptional regulation of all septins is complex, resulting in alternatively spliced variants.
• At least three septins (Septin 1, 2 and 4) are associated with a Tau-based paired helical filament core and may contribute to the formation of neurofibrillary tangle as integral constituents of paired helical filaments.
• Septin 3 (G-Septin), a GTPbinding protein, is highly expressed in brain and is regulated by protein kinase G in neurons.
• The human SEPT4 (H5/PNUTL2/CDCrREL-2) gene encodes ARTS (for apoptosis-related protein in the TGF B signaling pathway), which is expressed in many cells and acts to enhance cell death induced by TGF B or, to a lesser extent, by other apoptotic agents.
• ARTS is localized to mitochondria and translocates to the nucleus when apoptosis occurs.
• Applications:Suitable for use in Immunofluorescence, Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Immunofluorescence: 1:50-1:200Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.