Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins.
Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions.
Ribosomal Protein S7, also known as RPS7, is a 194aa protein that is a component of the 40S subunit.
Localized to the cytoplasm, Ribosomal Protein S7 belongs to the S7e family of ribosomal proteins and functions in protein synthesis.
Ribosomal Protein S7 interacts with MDM2 and is believed to negatively regulate the MDM2-mediated degradation of p53.
In addition, Ribosomal Protein S7 may play a role in ribosomal stress, linking ribosome biogenesis to cell death or cell cycle arrest.
Like most ribosomal proteins, Ribosomal Protein S7 exists as multiple processed pseudogenes that are scattered throughout the genome.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol.
Specificity：Recognizes human RPS7. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant protein corresponding to human RPS7.
