Relaxin 1 (also referred to as Relaxin or RLXH1) is a peptide hormone produced by the corpora lutea of the ovary during pregnancy in many mammalian species, including human.
The secretion of the hormone into the blood stream just before parturition results in a marked softening and lengthening of the pubic symphysis and a softening of the cervix, which facilitates the birth process.
By inhibiting uterine contractions, Relaxin 1 may influence the timing of parturition.
Like insulin, Relaxin 1 consists of two peptide chains, A and B, covalently linked by disulfide bonds.
By further analogy to insulin, the two peptides are synthesized as a single-chain precursor polypeptide with the B chain at the amino-terminus.
The gene that encodes the human Relaxin 1 protein maps to chromosome 9.
Relaxin 2, a related protein, is selectively expressed in the ovary during pregnancy.
The gene that encodes the human Relaxin 2 protein also maps to chromosome 9.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 15mM sodium azide.
Specificity：Recognizes human RLN2. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human RLN2.
