PSAT1 (phosphoserine aminotransferase 1), also known as phosphoserine aminotransferase, phosphohydroxythreonine aminotransferase, endometrial progesterone-induced protein, PSA, PSAT, EPIP or MGC1460, is a 370aa protein belonging to the class-V pyridoxal-phosphate- dependent aminotransferase family and serC subfamily.
PSAT1 catalyzes the second step in the L-serine synthesis pathway, converting 3-phosphohydroxypyruvate into 3-phosphoserine.
While highly expressed in pancreas, brain, kidney and liver, PSAT1 is expressed at very low levels in colon, testis, thymus and prostate.
There are two known isoforms of PSAT1 which result from alternative splicing events, and the gene encoding PSAT1 maps to human chromsome 9q21.2.
PSAT1 deficiency can cause phosphoserine aminotransferase deficiency (PSATD), whose symptoms include psychomotor retardation, intractable seizures, acquired microcephaly and hypertonia.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol.
Specificity：Recognizes human PSAT1. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant protein corresponding to human PSAT1.
