Olfactory receptors function by associating with odorant molecules to launch a neuronal response that elicits the perception of smell.
Olfactory receptor genes are unevenly dispersed among 51 loci on 21 human chromosomes, and are composed of 172 subfamilies.
OR6N1 (olfactory receptor, family 6, subfamily N, member 1), also known as olfactory receptor OR1-22, is a 312aa multi-pass membrane protein belonging to the G-protein coupled receptor 1 family.
As the largest family in the genome, the G-protein coupled receptor 1 family originated from single coding-exon genes.
Encoded by a gene that maps to human chromosome 1q23.1, OR6N1 functions as an odorant receptor.
Like many hormone and neurotransmitter receptors, OR6N1 shares a 7-transmembrane domain structure and recognizes G protein-mediated transduction of odorant signals.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 15mM sodium azide.
Specificity:Recognizes human OR6N1. Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to residues in human OR6N1.