NOM1 (nucleolar protein with MIF4G domain 1), also known as SGD1, is an 860aa protein that localizes to the nucleolus, where it plays a role in targeting PP1.
A member of the CWC22 family, NOM1 is expressed in skeletal muscle and heart, and contains one MI domain and a MIF4G domain.
The MIF4G typically functions in protein translation and may act as a binding site for members of the eIF4A family.
As such, NOM1 is thought to interact with eIF4AI, eIF4AII and eIF4AIII.
The gene encoding NOM1 maps to human chromosome 7, which houses over 1000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide.
Specificity:Recognizes human NOM1. Species Crossreactivity: rat
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Rt
Immunogen:Synthetic peptide corresponding to human NOM1.