84-4393-59　［取扱停止］NDUFA1 (NADH Dehydrogenase [ubiquinone] 1 alpha Subcomplex subunit 1, Complex I-MWFE, CI-MWFE, NDUFA1) 100ul　360854

特徴

• NDUFA1 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1), also known as ZNF183 or MWFE, is one of about 45 subunits comprising Complex I of the oxidative phosphorylation electron transport chain.
• Consisting of 70aa’s and expressed predominantly in skeletal muscle and heart, NDUFA1 functions as an accessory subunit of the multi-protein mitochondrial membrane respiratory chain NADH dehydrogenase complex (known as Complex I).
• Complex I plays an important role in the transfer of electrons from NADH to the respiratory chain, a process that is essential for cellular respiration.
• As a single-pass membrane protein, NDUFA1 localizes to the matrix side of the mitochondrial inner membrane and is a member of the complex I NDUFA1 subunit family.
• The gene encoding NDUFA1 maps to human chromosome Xq24 and mouse chromosome X A2.
• NDUFA1 defects may cause mitochondrial Complex I deficiency, a mitochondrial disorder with wide symptoms ranging from cardiomyopathy, myopathy, liver disease and neurological disorders.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.