This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors.
The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus.
The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation.
The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane.
Multiple transcript variants encoding different isoforms have been found for this gene.
The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19.
Applications:Suitable for use in Western Blot, Immunohistochemistry, and Immunofluorescence.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol.
Specificity:Recognizes human MYO1C. Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:IF IHC WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Recombinant protein corresponding to human MYO1C.