MTF-2 (metal response element binding transcription factor 2), also known as PCL2 (polycomb-like protein 2) or metal-response element DNA-binding protein M96, is a 593aa nuclear protein that binds the metal-regulating element (MRE) of the gene promoter for Metallothionein 1A.
Containing two PHD-type zinc fingers, MTF-2 exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 1p22.1.
Human chromosome 1 spans 260 million base pairs, contains over 3000 genes, comprises nearly 8% of the human genome and houses a large number of disease associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol.
Specificity：Recognizes human MTF2. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：IF IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant protein corresponding to full length human MTF2.
