Mitochondria have their own translation machinery for production of thirteen proteins that are required for oxidative phosphorylation.
MRP-L17 (39S ribosomal protein L17, mitochondrial), also known as LIP2 (LYST-interacting protein 2), is a 175aa protein that is a component of the large ribosomal subunit of the mitochondria.
Expressed in adipose tissue, adrenal gland and mammary gland, MRP-L17 is one of the 70 protein components of mitochondrial ribosomes that are encoded by the nuclear genome.The gene encoding MRP-L17 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.
Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 15mM sodium azide.
Specificity：Recognizes human MRPL17. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to human MRPL17.
