The MAGUK (membrane-associated guanylate kinase homologs) family of proteins contain multiple protein-binding domains and are involved in cell junction organization, tumor suppression and signaling.
The MAGUK family is divided into four subfamilies: DLG-like, ZO1-like, p55-like and LIN2-like.
MPP2 (membrane protein, palmitoylated 2), also known as MAGUK p55 subfamily member 2, discs large homolog 2 or DLG2, is a 576aa protein belonging to the MAGUK family that exists as three alternatively spliced isoforms.
MPP2 contains one guanylate kinase-like domain, a PDZ (DHR) domain, two L27 domains and a single SH3 domain.
The gene encoding MPP2 maps to the same segment of human chromosome 17 as MPP3, with whom MMP2 likely shares similar function and common structural organization.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol.
Specificity：Recognizes human MPP2. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant protein corresponding to human MPP2.
