BCDIN3 (bicoid-interacting protein 3), also known as MEPCE (methylphosphate capping enzyme), is a 689aa protein that contains one BIN3 domain and belongs to the methyltransferase superfamily.
Expressed in lung, brain, kidney, testis, mammary gland and cerebellum, BCDIN3 exists as a component of the multi-protein 7SK snRNP complex and functions as an S-adenosyl-L-methionine-dependent methyltransferase that stabilizes 7SK snRNA, specifically by adding a methylphosphate cap at the 5'-end of the snRNA.
Applications:Suitable for use in Immunofluorescence, Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunofluorescence: 1:50-1:200Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol.
Specificity：Recognizes human MEPCE.
Isotype：IgG
Calc Applications Abbrev：IF IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to human MEPCE.
