Med31 (mediator of RNA polymerase II transcription subunit 31), also known as Soh1 or CGI-125, is a 131aa protein that belongs to the mediator complex subunit 31 family.
Mediator proteins serve as connectors between transcriptional activators and basal transcription machinery.
Med31 is an evolutionary conserved coregulator of RNA polymerase II transcription and is a stable component of the Mediator complex.
It is involved in forming a scaffold with other regulatory proteins for the assembly of a functional preinitiation complex with RNA polymerase II and general transcription factors.
Med31 is required for normal levels of gene conversion during meiosis and contributes in the coordination of cellular processes by regulating the expression of larger sets of genes.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 15mM sodium azide.
Specificity：Recognizes human MED31. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to human MED31.
