The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes.
The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy.
MAGE genes encode for tumor-rejection antigens and are expressed in tumors of different histologic types as well as in normal testis and placenta.
MAGE-A9 (melanoma-associated antigen 9), also known as MAGE9 or CT1.9 (cancer/testis antigen 1.9), is a 315aa protein that contains one MAGE domain.
Like most MAGE family members, MAGE-A9 is expressed in several types of tumors, including lung cancer, breast cancer and melanoma, and is thought to play an important role in tumor progression and transformation.
Additionally, MAGE-A9 may be involved in embryonic development.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide.
Specificity：Recognizes human MAGEA9. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human MAGEA9.
